Cytokeratin 18 Monoclonal antibody, PBS Only

Cytokeratin 18 Monoclonal Antibody for WB, IF, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig

Applications

WB, IF, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

1G11C4

Cat No : 66187-1-PBS

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Synonyms

CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18



Planning an IHC experiment? We recommend our IHCeasy KRT18 Ready-To-Use IHC Kit. KRT18 primary antibody included.

产品信息

66187-1-PBS targets Cytokeratin 18 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Applications WB, IF, IHC, ELISA Application Description
Tested Reactivity human, mouse, rat, pig
Immunogen Cytokeratin 18 fusion protein Ag1260 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name keratin 18
Synonyms CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18
Calculated Molecular Weight 48 kDa
Observed Molecular Weight 48 kDa
GenBank Accession NumberBC000180
Gene Symbol KRT18
Gene ID (NCBI) 3875
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP05783
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

背景介绍

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.