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Anti-Human DDR1/CD167a Rabbit Recombinant Antibody

DDR1/CD167a Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241796D6

Cat no : 98200-1-RR

Print datasheet

Synonyms

DDR1, Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167

验证数据展示

  • FC experiment of MCF-7 using 98200-1-RR

    FC experiment of MCF-7 using 98200-1-RR

    1x10^6 MCF-7 cells (left) or HeLa cells (right) were surface stained with 0.25 ug Anti-Human DDR1/CD167a Rabbit Recombinant Antibody (98200-1-RR, Clone: 241796D6) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

经过测试的应用

Positive FC detected inMCF-7 cells
Planning an IHC experiment? We recommend our IHCeasy DDR1 Ready-To-Use IHC Kit. DDR1 primary antibody included.

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98200-1-RR targets DDR1/CD167a in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen FusionProtein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name discoidin domain receptor tyrosine kinase 1
Synonyms DDR1, Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167
Calculated Molecular Weight101kDa
GenBank Accession NumberNM_001297654.2
Gene Symbol DDR1
Gene ID (NCBI) 780
RRIDAB_3672333
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ08345-1
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

背景介绍

DDR1, or CD167a, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells.

实验方案

Product Specific Protocols
FC protocol for DDR1/CD167a antibody 98200-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols