验证数据展示
产品信息
67915-1-PBS targets DDX3 in WB, IHC, FC (Intra), Indirect ELISA applications and shows reactivity with human, rat samples.
经测试应用 | WB, IHC, FC (Intra), Indirect ELISA Application Description |
经测试反应性 | human, rat |
免疫原 | DDX3 fusion protein Ag29972 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked |
别名 | DDX3X, DDX14, DBX, CAP-Rf, ATP-dependent RNA helicase DDX3X |
计算分子量 | 73 kDa |
观测分子量 | 71-73 kDa |
GenBank蛋白编号 | BC011819 |
基因名称 | DDX3 |
Gene ID (NCBI) | 1654 |
RRID | AB_2918669 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | O00571 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DDX3X, also named DBX, DDX3, and HLP2, belongs to the DEAD-box helicase family and DDX3/DED1 subfamily. It is ATP-dependent RNA helicase. DDX3X acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. It is also involved in HIV-1 replication. DDX3X interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location. 73kd is the target band. 60-65kd is some other isoform. This antibody can bind both DDX3X and DDX3Y for the close sequences.