验证数据展示
产品信息
67111-1-PBS targets DLX5 in WB, IHC, ELISA applications and shows reactivity with Human, mouse, rat, pig samples.
经测试应用 | WB, IHC, ELISA Application Description |
经测试反应性 | Human, mouse, rat, pig |
免疫原 | DLX5 fusion protein Ag17040 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | distal-less homeobox 5 |
别名 | distal less homeobox 5, DLX5, Homeobox protein DLX 5 |
计算分子量 | 32 kDa |
观测分子量 | 33-38 kDa |
GenBank蛋白编号 | BC006226 |
基因名称 | DLX5 |
Gene ID (NCBI) | 1749 |
RRID | AB_2882415 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P56178 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DLX5 belongs to the DLX family of homeobox transcription factors (Dlx1, Dlx2, Dlx5 and Dlx6), which is expressed in overlapping domains at different stages of cell differentiation in the subpallium and controls differentiation of GABAergic neurons. DLX5 is an immediate early BMP-responsive transcriptional activator that essential for osteoblast differentiation. It can bind to and stimulate the homeodomain-response element of the ALPL and SP7 promoter. DLX5 can form homodimer with DLX2(~34kd) and heterodimer with MSX2(~29kd).