验证数据展示
产品信息
28149-1-PBS targets DMRT1 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, IF-P, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | DMRT1 fusion protein Ag28006 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | doublesex and mab-3 related transcription factor 1 |
Synonyms | |
Calculated Molecular Weight | 39 kDa |
Observed Molecular Weight | 39 kDa |
GenBank Accession Number | BC040847 |
Gene Symbol | DMRT1 |
Gene ID (NCBI) | 1761 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9Y5R6 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DMRT1, also named DMT1, belongs to the DMRT family. DMRT1 is one of the most conserved transcription factors in a variety of species and is involved in sex determination and germ cell differentiation. DMRT1 prevents the sexual switch from male to female, represses pluripotency, and balances mitosis versus meiosis. DMRT1 also maintains spermatogenesis and replenishes mGSCs by collaborating with Plzf and Sal-like protein 4 (PMID: 33420764). DMRT1 has 3 isoforms with the molecular mass of 18, 29, and 39 kDa.