验证数据展示
产品信息
28149-1-PBS targets DMRT1 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IF-P, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | DMRT1 fusion protein Ag28006 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | doublesex and mab-3 related transcription factor 1 |
别名 | |
计算分子量 | 39 kDa |
观测分子量 | 39 kDa |
GenBank蛋白编号 | BC040847 |
基因名称 | DMRT1 |
Gene ID (NCBI) | 1761 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9Y5R6 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DMRT1, also named DMT1, belongs to the DMRT family. DMRT1 is one of the most conserved transcription factors in a variety of species and is involved in sex determination and germ cell differentiation. DMRT1 prevents the sexual switch from male to female, represses pluripotency, and balances mitosis versus meiosis. DMRT1 also maintains spermatogenesis and replenishes mGSCs by collaborating with Plzf and Sal-like protein 4 (PMID: 33420764). DMRT1 has 3 isoforms with the molecular mass of 18, 29, and 39 kDa.