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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis using 68515-1-Ig (same clone as 68515-1-PBS)

    WB analysis using 68515-1-Ig (same clone as 68515-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68515-1-Ig (DSG2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68515-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP51241-1

    Cytometric bead array standard curve of MP51241-1

    Cytometric bead array standard curve of MP51241-1, DSG2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68515-1-PBS. Detection antibody: 68515-2-PBS. Standard:Ag20633. Range: 0.391-100 ng/mL.

DSG2 Monoclonal antibody, PBS Only (Capture)

DSG2 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 68515-1-PBS

Print datasheet

CloneNo. 1B8C3

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Cytometric bead array, Indirect ELISA

Synonyms

Desmoglein-2, Desmoglein 2, CDHF5, Cadherin family member 5, ARVD10

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 
100 μg

¥5800/ 100 μg

浓度: 1mg/ml

库存：1周货期

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Planning an IHC experiment? We recommend our IHCeasy DSG2 Ready-To-Use IHC Kit. DSG2 primary antibody included.

产品信息

68515-1-PBS targets DSG2 as part of a matched antibody pair:

MP51241-1: 68515-1-PBS capture and 68515-2-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen DSG2 fusion protein Ag20633 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name desmoglein 2
Synonyms Desmoglein-2, Desmoglein 2, CDHF5, Cadherin family member 5, ARVD10
Calculated Molecular Weight 1118 aa, 122 kDa
Observed Molecular Weight145-150 kDa
GenBank Accession NumberBC099655
Gene Symbol DSG2
Gene ID (NCBI) 1829
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ14126
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmosomal cadherins, consisting of four desmogleins (DSG1-4) and three desmocollins (DSC1-3) in humans, mediate adhesion through calcium-dependent homophilic/heterophilic interactions. DSG2 is a single-pass transmembrane glycoprotein that is widely expressed in epithelial and non-epithelial tissues, such as the intestine, epidermis, testis, and heart (PMID:21715983). Defects in DSG2 are the cause of familial arrhythmogenic right ventricular dysplasia type 10 (ARVD10), and genetic variations in DSG2 are the cause of susceptibility to cardiomyopathy dilated type 1BB (CMD1BB).