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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated DUSP11 Polyclonal antibody

DUSP11 Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-10204

Print datasheet

Synonyms

DUSP11, PIR1

验证数据展示

  • IF Staining of A431 using CL488-10204

    IF Staining of A431 using CL488-10204

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using CoraLite® Plus 488 DUSP11 antibody (CL488-10204) at dilution of 1:600.

经过测试的应用

Positive IF/ICC detected inA431 cells, HepG2 cells

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:300-1:1200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-10204 targets DUSP11 in IF/ICC applications and shows reactivity with human samples.

Tested Applications IF/ICC Application Description
Tested Reactivity human
Immunogen DUSP11 fusion protein Ag0276 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Synonyms DUSP11, PIR1
Calculated Molecular Weight 39 kDa
Observed Molecular Weight 39 kDa
GenBank Accession NumberBC000346
Gene Symbol DUSP11
Gene ID (NCBI) 8446
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO75319
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

DUSP11, also known as PIR1, is a unique member of atypical DUSPs which could bind directly to RNA and possess RNA 5'-triphosphatase and diphosphatase activities. DUSP11 converts the 5' triphosphate of microRNA precursors to a 5' monophosphate, and regulates cellular noncoding RNAs levels. In addition to a catalysis towards RNA, more evidence showed that DUSP11 could also dephosphorylate proteins.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 DUSP11 antibody CL488-10204Download protocol
Standard Protocols
Click here to view our Standard Protocols