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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 30256-1-AP (same clone as 30256-1-PBS)

    WB analysis using 30256-1-AP (same clone as 30256-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30256-1-AP (DUSP5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30256-1-PBS in a different storage buffer formulation.

  • IP experiment of A549 using 30256-1-AP (same clone as 30256-1-PBS)

    IP experiment of A549 using 30256-1-AP (same clone as 30256-1-PBS)

    IP result of anti-DUSP5 (IP:30256-1-AP, 4ug; Detection:30256-1-AP 1:500) with A549 cells lysate 1200 ug. This data was developed using the same antibody clone with 30256-1-PBS in a different storage buffer formulation.

DUSP5 Polyclonal antibody, PBS Only

DUSP5 Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 30256-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

30256-1-PBS targets DUSP5 in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IP, Indirect ELISA Application Description
Tested Reactivity human
Immunogen DUSP5 fusion protein Ag32997 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name dual specificity phosphatase 5
Synonyms
Calculated Molecular Weight42kd
Observed Molecular Weight 42 kDa
GenBank Accession NumberNM_004419
Gene Symbol DUSP5
Gene ID (NCBI) 1847
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ16690
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DUSP5 (Dual specificity protein phosphatase 5) is also named as VH3. DUSP5, a member of DUSPs superfamily, is located in the nucleus and plays crucially regulatory roles in the signaling pathway transduction (PMID: 34169608). DUSP5 promotes the osteogenic differentiation of mesenchymal stromal cells (MSCs) by repressing SMAD1 signaling pathway in a SCP1/2‐dependent manner (PMID: 34169608). DUSP5, which specifically dephosphorylates extracellular signal-regulated kinase (ERK1/2), blocks pulmonary vascular smooth muscle cell proliferation (PMID: 34142888). DUSP5, an ERK1/2-specific endogenous phosphatase, was expressed at low levels in CRC (PMID: 36526622). DUSP5, a member of the DUSP subfamily, is known to regulate cellular inflammation (PMID: 33361528).