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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 30256-1-AP (same clone as 30256-1-PBS)

    WB analysis using 30256-1-AP (same clone as 30256-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30256-1-AP (DUSP5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30256-1-PBS in a different storage buffer formulation.

  • IP experiment of A549 using 30256-1-AP (same clone as 30256-1-PBS)

    IP experiment of A549 using 30256-1-AP (same clone as 30256-1-PBS)

    IP result of anti-DUSP5 (IP:30256-1-AP, 4ug; Detection:30256-1-AP 1:500) with A549 cells lysate 1200 ug. This data was developed using the same antibody clone with 30256-1-PBS in a different storage buffer formulation.

DUSP5 Polyclonal antibody, PBS Only

DUSP5 Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 30256-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

30256-1-PBS targets DUSP5 in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原 DUSP5 fusion protein Ag32997 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 dual specificity phosphatase 5
别名
计算分子量42kd
观测分子量 42 kDa
GenBank蛋白编号NM_004419
基因名称 DUSP5
Gene ID (NCBI) 1847
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ16690
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DUSP5 (Dual specificity protein phosphatase 5) is also named as VH3. DUSP5, a member of DUSPs superfamily, is located in the nucleus and plays crucially regulatory roles in the signaling pathway transduction (PMID: 34169608). DUSP5 promotes the osteogenic differentiation of mesenchymal stromal cells (MSCs) by repressing SMAD1 signaling pathway in a SCP1/2‐dependent manner (PMID: 34169608). DUSP5, which specifically dephosphorylates extracellular signal-regulated kinase (ERK1/2), blocks pulmonary vascular smooth muscle cell proliferation (PMID: 34142888). DUSP5, an ERK1/2-specific endogenous phosphatase, was expressed at low levels in CRC (PMID: 36526622). DUSP5, a member of the DUSP subfamily, is known to regulate cellular inflammation (PMID: 33361528).