验证数据展示
产品信息
67657-1-PBS targets Destrin in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | Human, mouse, rat, pig |
| 免疫原 | Destrin fusion protein Ag1402 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | destrin (actin depolymerizing factor) |
| 别名 | ACTDP, Actin depolymerizing factor, ADF, bA462D18.2, Destrin, DSN, DSTN |
| 计算分子量 | 19 kDa |
| 观测分子量 | 18-19 kDa |
| GenBank蛋白编号 | BC009477 |
| 基因名称 | Destrin |
| Gene ID (NCBI) | 11034 |
| RRID | AB_2918496 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P60981 |
| 储存缓冲液 | PBS Only |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Destrin (also known as actin depolymerization factor, ADF) is an actin-binding protein contributing to cytoskeletal dynamics by promoting rapid actin filament disassembly. By regulating actin cytoskeletal reorganization it plays an important role in the formation of filopodia, which further promotes tumor cell invasion and metastasis. Destrin has been reported to be overexpressed in primary colon cancer.