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Dysbindin Polyclonal antibody, PBS Only

Dysbindin Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11132-1-PBS

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Synonyms

验证数据展示

  • WB analysis of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    WB analysis of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 11132-1-AP (Dysbindin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11132-1-AP (Dysbindin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11132-1-AP (Dysbindin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

产品信息

11132-1-PBS targets Dysbindin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Dysbindin fusion protein Ag1613 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name dystrobrevin binding protein 1
Synonyms
Calculated Molecular Weight 351 aa, 39 kDa
Observed Molecular Weight 48 kDa, 36 kDa
GenBank Accession NumberBC011912
Gene Symbol Dysbindin
Gene ID (NCBI) 84062
RRIDAB_11182503
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96EV8
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Dysbindin, encoded by DTNBP1 (dystrobrevin binding protein 1), is a synaptic protein which is expressed in diverse neuronal populations throughout the brain. Genetic variation in DTNBP1 is associated with schizophrenia. Reduced expression of dysbindin has been reported in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia cases. Several isoforms of dysbindin exist: 48-50 kDa of dysbindin-1A, 35-38 kDa of dysbindin-1B, and 30-32 kDa of dysbindin-1C. This antibody recognizes all of isoforms of dysbindin. (19617633)