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  • Featured Product
  • KD/KO Validated

EI24 Polyclonal antibody, PBS Only

EI24 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 20456-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 20456-1-AP (same clone as 20456-1-PBS)

    WB analysis using 20456-1-AP (same clone as 20456-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20456-1-AP (EI24 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20456-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 20456-1-AP (same clone as 20456-1-PBS)

    IHC staining of human colon cancer using 20456-1-AP (same clone as 20456-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 20456-1-AP (EI24 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20456-1-PBS in a different storage buffer formulation.

产品信息

20456-1-PBS targets EI24 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen EI24 fusion protein Ag14169 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name etoposide induced 2.4 mRNA
Synonyms
Calculated Molecular Weight 340 aa, 39 kDa
Observed Molecular Weight 40-45 kDa
GenBank Accession NumberBC002390
Gene Symbol EI24
Gene ID (NCBI) 9538
RRIDAB_10858326
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO14681
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Ei24 is an ER-localized protein originally identified as a p53-induced proapoptotic gene in etoposide-treated NIH3T3 cells. It has been shown to be able to bind to the antiapoptotic protein Bcl-2 (PMID: 15781622), play a role in autophagy (PMID: 23074225), and induce proliferate arrest/apoptosis (PMID: 10594026). Ei24 can bind specifically to IMPβ1 and IMPα2 to impede their normal role in nuclear import (PMID: 24821838).