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验证数据展示

  • WB analysis using 20456-1-AP (same clone as 20456-1-PBS)

    WB analysis using 20456-1-AP (same clone as 20456-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20456-1-AP (EI24 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20456-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 20456-1-AP (same clone as 20456-1-PBS)

    IHC staining of human colon cancer using 20456-1-AP (same clone as 20456-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 20456-1-AP (EI24 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20456-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

EI24 Polyclonal antibody, PBS Only

EI24 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 20456-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

20456-1-PBS targets EI24 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 EI24 fusion protein Ag14169 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 etoposide induced 2.4 mRNA
别名
计算分子量 340 aa, 39 kDa
观测分子量 40-45 kDa
GenBank蛋白编号BC002390
基因名称 EI24
Gene ID (NCBI) 9538
RRIDAB_10858326
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO14681
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Ei24 is an ER-localized protein originally identified as a p53-induced proapoptotic gene in etoposide-treated NIH3T3 cells. It has been shown to be able to bind to the antiapoptotic protein Bcl-2 (PMID: 15781622), play a role in autophagy (PMID: 23074225), and induce proliferate arrest/apoptosis (PMID: 10594026). Ei24 can bind specifically to IMPβ1 and IMPα2 to impede their normal role in nuclear import (PMID: 24821838).