验证数据展示
产品信息
67799-1-PBS targets EIF4A2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | EIF4A2 fusion protein Ag9085 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | eukaryotic translation initiation factor 4A, isoform 2 |
Synonyms | EIF4A, eIF 4A II, EC:3.6.4.13, DDX2B, BM 010 |
Calculated Molecular Weight | 408 aa, 46 kDa |
Observed Molecular Weight | 46 kDa |
GenBank Accession Number | BC012547 |
Gene Symbol | EIF4A2 |
Gene ID (NCBI) | 1974 |
RRID | AB_2918563 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q14240 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Eukaryotic initiation factor 4A (EIF4A) has an essential role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins, as EIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. EIF4A2 is a ATP-dependent RNA helicase, which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.