Endoglin/CD105 Monoclonal antibody, PBS Only (Detector)

Endoglin/CD105 Monoclonal Antibody for IF/ICC, Cytometric bead array, Indirect ELISA
Cat No. 68748-2-PBS

产品说明书

CloneNo. 2D4A5

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IF/ICC, Cytometric bead array, Indirect ELISA

CD105, 2D4A5, HHT1, ENG, Endoglin

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy Endoglin/CD105 Ready-To-Use IHC Kit. Endoglin/CD105 primary antibody included.

产品信息

68748-2-PBS targets Endoglin/CD105 as part of a matched antibody pair:

MP50103-1: 68748-1-PBS capture and 68748-2-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 IF/ICC, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 endoglin
别名 CD105, 2D4A5, HHT1, ENG, Endoglin
计算分子量 71 kDa
GenBank蛋白编号BC014271
基因名称 CD105
Gene ID (NCBI) 2022
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP17813
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

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