验证数据展示
产品信息
84732-2-PBS targets EPB41L4B as part of a matched antibody pair:
MP01525-1: 84732-2-PBS capture and 84732-1-PBS detection (validated in Cytometric bead array)
MP01525-2: 84732-2-PBS capture and 84732-3-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
经测试应用 | WB, Cytometric bead array, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | EPB41L4B fusion protein Ag36353 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | erythrocyte membrane protein band 4.1 like 4B |
别名 | 242186G4, Band 4.1 like protein 4B, CG1, EHM2, FERM containing protein CG1 |
计算分子量 | 99kDa |
观测分子量 | 100 kDa |
GenBank蛋白编号 | NM_00138562 |
基因名称 | EPB41L4B |
Gene ID (NCBI) | 54566 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9H329 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The 4.1 proteins, encoded by the EPB41 (erythrocyte protein band 4.1) genes, are components of the cortical cytoskeleton underlying the cell membrane. The family of 4.1 proteins consists of the eponymous 4.1R protein first identified in erythrocytes (gene: EPB41), 4.1N (EPB41L1), 4.1G (EPB41L2), 4.1B (EPB41L3) as well as the less closely related members NBL4 (EPB41L4A), EHM2 (EPB41L4B) and EPB41L5 (EPB41L5). EHM2 is conspicuous in tumor cells with high migratory potential, such as metastatic melanoma and fibrosarcoma cells. In prostate cancer, EHM2 has been reported to be overexpressed and to diminish adhesion of prostate cancer cells to collagen. (PMID: 20860828)