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ER Recombinant antibody, PBS Only

ER Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241825D5

Cat no : 84564-4-PBS

Print datasheet

Synonyms

ESR1, ESR, ERα, ER-alpha, Era

验证数据展示

  • WB analysis using 84564-4-RR (same clone as 84564-4-PBS)

    WB analysis using 84564-4-RR (same clone as 84564-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84564-4-RR (ER antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84564-4-PBS in a different storage buffer formulation.

  • IHC staining of human ovary cancer using 84564-4-RR (same clone as 84564-4-PBS)

    IHC staining of human ovary cancer using 84564-4-RR (same clone as 84564-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 84564-4-RR (ER antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84564-4-PBS in a different storage buffer formulation.

产品信息

84564-4-PBS targets ER in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name estrogen receptor 1
Synonyms ESR1, ESR, ERα, ER-alpha, Era
Calculated Molecular Weight 595 aa, 66 kDa
Observed Molecular Weight66 kDa
GenBank Accession NumberBC128573
Gene Symbol ER
Gene ID (NCBI) 2099
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP03372
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The estrogen receptor (ESR, ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. ESR1, also known as ESR or NR3A1, belongs to the nuclear hormone receptor family and NR3 subfamily. It is a nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. ESR1 can activate the transcriptional activity of TFF1.[PMID: 11731608,10970861]