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ERAP2 Monoclonal antibody, PBS Only

ERAP2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, Rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2B11A2

Cat no : 67477-1-PBS

Print datasheet

Synonyms

ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP

验证数据展示

  • WB analysis of A549 using 67477-1-Ig (same clone as 67477-1-PBS)

    WB analysis of A549 using 67477-1-Ig (same clone as 67477-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

  • WB analysis using 67477-1-Ig (same clone as 67477-1-PBS)

    WB analysis using 67477-1-Ig (same clone as 67477-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67477-1-Ig (ERAP2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67477-1-PBS in a different storage buffer formulation.

产品信息

67477-1-PBS targets ERAP2 in WB, Indirect ELISA applications and shows reactivity with Human, Rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, Rat
Immunogen ERAP2 fusion protein Ag30061 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name endoplasmic reticulum aminopeptidase 2
Synonyms ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP
Calculated Molecular Weight 110 kDa
Observed Molecular Weight 110-120 kDa
GenBank Accession NumberBC065240
Gene Symbol ERAP2
Gene ID (NCBI) 64167
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ6P179
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ERAP2(Endoplasmic reticulum aminopeptidase 2) is also named as LRAP(Leukocyte-derived arginine aminopeptidase). It plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. ERAP2 can form heterodimers with ERAP1(PMID:15908954). Defects in the expression of ERAP2 may cause improper antigen processing, possibly leading to favor tumor escape from the immune surveillance. ERAP2 has the calculated molecular mass of 105-110 kDa, and apparent molecular mass of 120 kDa duo to the glycosylation.