ERCC1 Monoclonal antibody, PBS Only

ERCC1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 66275-1-PBS

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CloneNo. 1H4D5

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

COFS4, ERCC1, UV20

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -


产品信息

66275-1-PBS targets ERCC1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen ERCC1 fusion protein Ag6417 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
Synonyms COFS4, ERCC1, UV20
Calculated Molecular Weight 33 kDa
Observed Molecular Weight 38 kDa
GenBank Accession NumberBC052813
Gene Symbol ERCC1
Gene ID (NCBI) 2067
RRIDAB_2881658
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP07992
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11, XPF and ERCC4, which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1, together with RRM1, are determinants of survival after surgical treatment of early-stage, non-small-cell lung cancer. (Ref: Simon, ER. 2005)

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