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ESRP2 Polyclonal antibody, PBS Only

ESRP2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 23117-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 23117-1-AP (same clone as 23117-1-PBS)

    WB analysis using 23117-1-AP (same clone as 23117-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23117-1-AP (ESRP2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23117-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 23117-1-AP (same clone as 23117-1-PBS)

    IHC staining of human breast cancer using 23117-1-AP (same clone as 23117-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 23117-1-AP (ESRP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23117-1-PBS in a different storage buffer formulation.

产品信息

23117-1-PBS targets ESRP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen ESRP2 fusion protein Ag19436 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name epithelial splicing regulatory protein 2
Synonyms
Calculated Molecular Weight 727 aa, 78 kDa
Observed Molecular Weight 78 kDa
GenBank Accession NumberBC030146
Gene Symbol ESRP2
Gene ID (NCBI) 80004
RRIDAB_2879213
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9H6T0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ESRP2 (Epithelial Splicing Regulatory Protein 2), also known as RBM35B(RNA binding motif protein 35B), is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family of RNA binding proteins. ESRP2 plays a role in the regulation of alternative splicing events of pre-mRNAs(PMID: 27401076). Overexpression of ESRP2 has been described in various malignant tumors, such as pancreatic ductal adenocarcinoma, oral squamous carcinoma, ovarian cancer, and luminal-type breast cancer(PMID: 33339518).