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ETV6 Monoclonal antibody, PBS Only

ETV6 Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

2A5A2

Cat no : 67579-1-PBS

Print datasheet

Synonyms

ETS related protein Tel1, ETS translocation variant 6, ets variant 6, ETV6, TEL, TEL/ABL, TEL1, Transcription factor ETV6

验证数据展示

  • IHC staining of human breast cancer using 67579-1-Ig (same clone as 67579-1-PBS)

    IHC staining of human breast cancer using 67579-1-Ig (same clone as 67579-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67579-1-Ig (ETV6 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67579-1-PBS in a different storage buffer formulation.

  • WB analysis of Jurkat using 67579-1-Ig (same clone as 67579-1-PBS)

    WB analysis of Jurkat using 67579-1-Ig (same clone as 67579-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 67579-1-Ig (ETV6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67579-1-PBS in a different storage buffer formulation.

  • WB analysis of K-562 using 67579-1-Ig (same clone as 67579-1-PBS)

    WB analysis of K-562 using 67579-1-Ig (same clone as 67579-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67579-1-Ig (ETV6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67579-1-PBS in a different storage buffer formulation.

67579-1-Ig

产品信息

67579-1-PBS targets ETV6 in WB, IHC, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity Human
Immunogen ETV6 fusion protein Ag30054 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name ets variant 6
Synonyms ETS related protein Tel1, ETS translocation variant 6, ets variant 6, ETV6, TEL, TEL/ABL, TEL1, Transcription factor ETV6
Calculated Molecular Weight 452 aa, 53 kDa
Observed Molecular Weight60 kDa
GenBank Accession NumberBC043399
Gene Symbol ETV6
Gene ID (NCBI) 2120
RRIDAB_2918493
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP41212
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ETV6(ETS Variant Transcription Factor 6), also known as TEL, is a Protein Coding gene. ETV6 is a member of the ETS family of transcription factors encoded by the ETS variant 6 gene (ETV6), located on chromosome 12p13.2. ETV6 protein contains 3 domains: a) the pointed N-terminal (i.e. PNT) domain which forms oligomer partners with itself as well as other transcription factors (e.g. FLI1) and is required for ETV6's transcriptional repressing activity; b) the central regulatory domain; and c) the C-terminal DNA-binding domain(PMID: 22578774). ETV6 is highly expressed in early hematopoietic progenitor cells(HPCs) and is essential for hematopoiesis in the bone marrow(PMID: 31248877).