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验证数据展示

  • IHC staining of human breast cancer using 67579-1-Ig (same clone as 67579-1-PBS)

    IHC staining of human breast cancer using 67579-1-Ig (same clone as 67579-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 67579-1-Ig (ETV6 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67579-1-PBS in a different storage buffer formulation.

  • WB analysis of Jurkat using 67579-1-Ig (same clone as 67579-1-PBS)

    WB analysis of Jurkat using 67579-1-Ig (same clone as 67579-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 67579-1-Ig (ETV6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67579-1-PBS in a different storage buffer formulation.

  • WB analysis of K-562 using 67579-1-Ig (same clone as 67579-1-PBS)

    WB analysis of K-562 using 67579-1-Ig (same clone as 67579-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67579-1-Ig (ETV6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67579-1-PBS in a different storage buffer formulation.

ETV6 Monoclonal antibody, PBS Only

ETV6 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 67579-1-PBS

产品说明书

CloneNo. 2A5A2

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, IHC, ELISA

别名

ETS related protein Tel1, ETS translocation variant 6, ets variant 6, ETV6, TEL, TEL/ABL, TEL1, Transcription factor ETV6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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67579-1-Ig

产品信息

67579-1-PBS targets ETV6 in WB, IHC, ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 Human
免疫原 ETV6 fusion protein Ag30054 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 ets variant 6
别名 ETS related protein Tel1, ETS translocation variant 6, ets variant 6, ETV6, TEL, TEL/ABL, TEL1, Transcription factor ETV6
计算分子量 452 aa, 53 kDa
观测分子量60 kDa
GenBank蛋白编号BC043399
基因名称 ETV6
Gene ID (NCBI) 2120
RRIDAB_2918493
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP41212
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ETV6(ETS Variant Transcription Factor 6), also known as TEL, is a Protein Coding gene. ETV6 is a member of the ETS family of transcription factors encoded by the ETS variant 6 gene (ETV6), located on chromosome 12p13.2. ETV6 protein contains 3 domains: a) the pointed N-terminal (i.e. PNT) domain which forms oligomer partners with itself as well as other transcription factors (e.g. FLI1) and is required for ETV6's transcriptional repressing activity; b) the central regulatory domain; and c) the C-terminal DNA-binding domain(PMID: 22578774). ETV6 is highly expressed in early hematopoietic progenitor cells(HPCs) and is essential for hematopoiesis in the bone marrow(PMID: 31248877).