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EXOC3L2 Monoclonal antibody, PBS Only

EXOC3L2 Monoclonal Antibody for WB,Indirect ELISA,IF

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB,Indirect ELISA,IF

Conjugate

Unconjugated

CloneNo.

3C1C2

Cat No : 66537-1-PBS

Print datasheet

Synonyms

EXOC3L2, XTP7

验证数据展示

  • WB analysis of HUVEC using 66537-1-Ig (same clone as 66537-1-PBS)

    WB analysis of HUVEC using 66537-1-Ig (same clone as 66537-1-PBS)

    HUVEC, HEK-293 and U-251 cells were subjected to SDS PAGE followed by western blot with 66537-1-Ig (EXOC3L2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66537-1-PBS in a different storage buffer formulation.

  • IF Staining of HUVEC using 66537-1-Ig (same clone as 66537-1-PBS)

    IF Staining of HUVEC using 66537-1-Ig (same clone as 66537-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HUVEC cells using EXOC3L2 antibody (66537-1-Ig, Clone: 3C1C2 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66537-1-PBS in a different storage buffer formulation.

产品信息

66537-1-PBS targets EXOC3L2 in WB, IF, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB,Indirect ELISA,IF Application Description
Tested Reactivity Human
Immunogen EXOC3L2 fusion protein Ag26912 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name exocyst complex component 3-like 2
Synonyms EXOC3L2, XTP7
Calculated Molecular Weight 46 kDa
Observed Molecular Weight 46 kDa
GenBank Accession NumberBC104947
Gene Symbol EXOC3L2
Gene ID (NCBI) 90332
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ2M3D2
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

The exocyst is a protein complex that ensures spatial targeting of exocytotic vesicles to the plasma membrane. Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells (PMID: 21566143). The gene of human EXOC3L2 maps to chromosome 19q13.32 and encodes a deduced 409-amino acid protein with a calculated molecular mass of about 46 kDa. Mouse Exoc3l2 gene encodes an approximately 250-amino acid protein that lacks the N-terminal domain of human EXOC3L2. Mutations in EXOC3L2 gene may be associated with Alzheimer's disease.