CoraLite® Plus 488-conjugated EXOC3L2 Monoclonal antibody
EXOC3L2 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
3C1C2
验证数据展示
经过测试的应用
Positive IF/ICC detected in | HUVEC cells |
For other applications, we recommend the unconjugated version of this antibody, 66537-1-Ig
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-66537 targets EXOC3L2 in IF/ICC applications and shows reactivity with Human samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | Human |
Immunogen | EXOC3L2 fusion protein Ag26912 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | exocyst complex component 3-like 2 |
Synonyms | EXOC3L2, FLJ36147, XTP7 |
Calculated Molecular Weight | 46 kDa |
Observed Molecular Weight | 46 kDa |
GenBank Accession Number | BC104947 |
Gene Symbol | EXOC3L2 |
Gene ID (NCBI) | 90332 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q2M3D2 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The exocyst is a protein complex that ensures spatial targeting of exocytotic vesicles to the plasma membrane. Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells (PMID: 21566143). The gene of human EXOC3L2 maps to chromosome 19q13.32 and encodes a deduced 409-amino acid protein with a calculated molecular mass of about 46 kDa. Mouse Exoc3l2 gene encodes an approximately 250-amino acid protein that lacks the N-terminal domain of human EXOC3L2. Mutations in EXOC3L2 gene may be associated with Alzheimer's disease.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 EXOC3L2 antibody CL488-66537 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |