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Host
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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis using 82993-6-RR (same clone as 82993-6-PBS)

    WB analysis using 82993-6-RR (same clone as 82993-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82993-6-RR (Endoglin/CD105 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82993-6-PBS in a different storage buffer formulation.

  • IHC staining of human ovary cancer using 82993-6-RR (same clone as 82993-6-PBS)

    IHC staining of human ovary cancer using 82993-6-RR (same clone as 82993-6-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 82993-6-RR (Endoglin/CD105 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 82993-6-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Endoglin/CD105 antibody included

Endoglin/CD105 Recombinant antibody, PBS Only

Endoglin/CD105 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 82993-6-PBS

产品说明书

CloneNo. 241196G9

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

CD105, 241196G9, HHT1, ENG, Endoglin

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy Endoglin/CD105 Ready-To-Use IHC Kit. Endoglin/CD105 primary antibody included.

产品信息

82993-6-PBS targets Endoglin/CD105 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 endoglin
别名 CD105, 241196G9, HHT1, ENG, Endoglin
计算分子量 71 kDa
观测分子量75-90 kDa
GenBank蛋白编号BC014271
基因名称 CD105
Gene ID (NCBI) 2022
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP17813
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)