FITC Plus Anti-Human Endoglin/CD105 Rabbit Recombinant Antibody
Endoglin/CD105 Uni-rAbTM Recombinant Antibody for FC
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
FC
Conjugate
FITC Plus Fluorescent Dye
CloneNo.
230047E5
验证数据展示
经过测试的应用
Positive FC detected in | human PBMCs |
Planning an IHC experiment? We recommend our IHCeasy CD105 Ready-To-Use IHC Kit. CD105 primary antibody included.
推荐稀释比
Application | Dilution |
---|---|
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
FITC-98013 targets Endoglin/CD105 in FC applications and shows reactivity with Human samples.
Tested Applications | FC Application Description |
Tested Reactivity | Human |
Immunogen | Recombinant protein 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | endoglin |
Synonyms | CD105, END, Endoglin, ENG, HHT1, ORW, ORW1 |
Calculated Molecular Weight | 71 kDa |
GenBank Accession Number | BC014271 |
Gene Symbol | CD105 |
Gene ID (NCBI) | 2022 |
Conjugate | FITC Plus Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 495 nm / 524 nm |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P17813 |
Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA. |
Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodeling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)
实验方案
Product Specific Protocols | |
---|---|
FC protocol for FITC Plus Endoglin/CD105 antibody FITC-98013 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |