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验证数据展示

  • IHC staining of human thyroid cancer using 12176-1-AP (same clone as 12176-1-PBS)

    IHC staining of human thyroid cancer using 12176-1-AP (same clone as 12176-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 12176-1-AP (FAM107A antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FAM107A antibody included
  • IF Staining of MCF-7 using 12176-1-AP (same clone as 12176-1-PBS)

    IF Staining of MCF-7 using 12176-1-AP (same clone as 12176-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using FAM107A antibody (12176-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 12176-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

FAM107A Polyclonal antibody, PBS Only

FAM107A Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 12176-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF/ICC, Indirect ELISA

别名

TU3A, DRR1, Down-regulated in renal cell carcinoma 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy FAM107A Ready-To-Use IHC Kit. FAM107A primary antibody included.

产品信息

12176-1-PBS targets FAM107A in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 FAM107A fusion protein Ag2820 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 family with sequence similarity 107, member A
别名 TU3A, DRR1, Down-regulated in renal cell carcinoma 1
计算分子量 144 aa, 17 kDa
GenBank蛋白编号BC010561
基因名称 FAM107A
Gene ID (NCBI) 11170
RRIDAB_2877832
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO95990
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FAM107A, also named as TU3A, encodes a 144 amino-acid protein, which contains a coiled-coil domain and a nuclear localization signal. FAM107A as a transcription factor regulates some gene transcription and signal transduction in cell. With the exception of peripheral blood cells, FAM107A is widely expressed in normal tissues, but shows significant loss of expression in renal cell carcinomas and frequent loss of expression in cervical, gastric, ovarian and non small cell lung cancers. Transfection of FAM107A mRNA into cancer cell line inhibits cell growth and proliferation, supporting the evidence that the gene functions as an important tumor suppressor.