FAM38B Recombinant antibody

FAM38B Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 83488-4-RR

产品说明书

CloneNo. 240406E5

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

Piezo2, Transmembrane protein C18orf30, C18orf30, 240406E5

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells
Positive FC (Intra) detected inA431 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

83488-4-RR targets FAM38B in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 FAM38B fusion protein Ag24528 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 family with sequence similarity 38, member B
别名 Piezo2, Transmembrane protein C18orf30, C18orf30, 240406E5
计算分子量 318 kDa
观测分子量250-310 kDa, 80 kDa
GenBank蛋白编号AB527139
基因名称 FAM38B
Gene ID (NCBI) 63895
RRIDAB_3671114
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9H5I5
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FAM38B, also named as PIEZO2, is a mechanosensitive, rapidly inactivating (RI) ion channel which is open and converts the mechanical stimulus signals into bioelectrical signals after stimulated by mechanical signals. FAM38B has been recently identified in dorsal root ganglion (DRG) neurons to mediate tactile transduction. It plays an important role in the biological process, maintaining cell metabolism and cell migration. Loss-of-function mutations in the human FAM38B gene cause an autosomal recessive syndrome of muscular atrophy with perinatal respiratory distress, arthrogryposis, and scoliosis.The 80 kDa band detected by SDS-PAGE can be caused by alternative splicing (PMID: 34335288, 37227654).

实验方案

Product Specific Protocols
WB protocol for FAM38B antibody 83488-4-RRDownload protocol
FC protocol for FAM38B antibody 83488-4-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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