验证数据展示
产品信息
84557-1-PBS targets FATP5/SLC27A5 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | FATP5/SLC27A5 fusion protein Ag18276 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | solute carrier family 27 (fatty acid transporter), member 5 |
别名 | FATP5, SLC27A5, Bile acyl-CoA synthetase, Bile acid-CoA ligase, BA-CoA ligase |
计算分子量 | 690 aa, 75 kDa |
观测分子量 | 70-75 kDa |
GenBank蛋白编号 | BC148807 |
基因名称 | FATP5/SLC27A5 |
Gene ID (NCBI) | 10998 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q9Y2P5 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC27A5, also known as FATP5, ACSVL6, and BAL, is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty acids containing 24- and 26-carbons(PMID: 10479480). FATP5 mediates the import of long-chain fatty acids (LCFA) by facilitating their transport across cell membranes (PubMed:20448275). FATP5 is associated with endoplasmic reticulum but not with peroxisomes, and its primary role is in fatty acid elongation or complex lipid synthesis. FATP5 is exclusively expressed by the liver and localized to the basal plasma membrane of hepatocytes (PMID:16618416).