验证数据展示
产品信息
67972-1-PBS targets FDPS in WB, Indirect ELISA applications and shows reactivity with Human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | Human |
| 免疫原 | FDPS fusion protein Ag9247 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) |
| 别名 | FDPS, FPP synthase, FPPS, FPS, KIAA1293 |
| 计算分子量 | 419 aa, 48 kDa |
| 观测分子量 | 38-39 kDa |
| GenBank蛋白编号 | BC010004 |
| 基因名称 | FDPS |
| Gene ID (NCBI) | 2224 |
| RRID | AB_2918722 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P14324 |
| 储存缓冲液 | PBS Only |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FPPS (also known as FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression.