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FDPS Monoclonal antibody, PBS Only

FDPS Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3B8A7

Cat no : 67972-1-PBS

Print datasheet

Synonyms

FDPS, FPP synthase, FPPS, FPS, KIAA1293

验证数据展示

  • WB analysis using 67972-1-Ig (same clone as 67972-1-PBS)

    WB analysis using 67972-1-Ig (same clone as 67972-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67972-1-Ig (FDPS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 67972-1-PBS in a different storage buffer formulation.

产品信息

67972-1-PBS targets FDPS in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen FDPS fusion protein Ag9247 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
Synonyms FDPS, FPP synthase, FPPS, FPS, KIAA1293
Calculated Molecular Weight 419 aa, 48 kDa
Observed Molecular Weight38-39 kDa
GenBank Accession NumberBC010004
Gene Symbol FDPS
Gene ID (NCBI) 2224
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP14324
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FPPS (also known as FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression.