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FDPS Monoclonal antibody

FDPS Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

3B8A7

Cat no : 67972-1-Ig

Print datasheet

Synonyms

FDPS, FPP synthase, FPPS, FPS, KIAA1293

验证数据展示

  • WB analysis using 67972-1-Ig

    WB analysis using 67972-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 67972-1-Ig (FDPS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control.

经过测试的应用

Positive WB detected inA431 cells, HepG2 cells, HeLa cells, HEK-293 cells, Jurkat cells, K-562 cells
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

67972-1-Ig targets FDPS in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human
Immunogen FDPS fusion protein Ag9247 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
Synonyms FDPS, FPP synthase, FPPS, FPS, KIAA1293
Calculated Molecular Weight 419 aa, 48 kDa
Observed Molecular Weight38-39 kDa
GenBank Accession NumberBC010004
Gene Symbol FDPS
Gene ID (NCBI) 2224
RRIDAB_2918722
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP14324
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FPPS (also known as FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression.

实验方案

Product Specific Protocols
WB protocol for FDPS antibody 67972-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols