验证数据展示
产品信息
25058-1-PBS targets FEV in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | FEV fusion protein Ag20647 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | FEV (ETS oncogene family) |
别名 | |
计算分子量 | 25 kDa |
观测分子量 | 25 kDa |
GenBank蛋白编号 | BC023511 |
基因名称 | FEV |
Gene ID (NCBI) | 54738 |
RRID | AB_2879877 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q99581 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FEV belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.