验证数据展示
产品信息
84544-1-PBS targets FFAR2 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IF-P, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | Peptide 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | free fatty acid receptor 2 |
别名 | GPCR43, G protein coupled receptor 43, free fatty acid receptor 2, FFA2R, FFA2 |
计算分子量 | 330 aa, 37 kDa |
观测分子量 | 37 kDa |
GenBank蛋白编号 | BC096198 |
基因名称 | FFAR2 |
Gene ID (NCBI) | 2867 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | O15552 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Free fatty acid receptors (FFAR) play significant roles in various physiological processes through interaction with their ligands, fatty acids. Free fatty acid receptor 2 (FFAR2, also known as FFA2 or GPR43) is a receptor for short-chain fatty acids (SCFAs) and plays a role in the regulation of whole-body energy homeostasis and intestinal immunity (PMID: 12684041). It has been considered a therapeutic target for metabolic and inflammatory conditions (PMID: 23589301). FFAR2 has a calculated molecular weight of 37 kDa and can be glycosylated. The higher apparent molecular weight of 50 kDa has been reported, probably due to glycosylation (PMID: 31707282; 28131568).