验证数据展示
经过测试的应用
| Positive IF/ICC detected in | C2C12 cells |
For other applications, we recommend the unconjugated version of this antibody, 11343-1-AP
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL647-11343 targets FGFR1OP in IF/ICC applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IF/ICC Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | FGFR1OP fusion protein Ag1891 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | FGFR1 oncogene partner |
| 别名 | FGFR1 oncogene partner, FGFR1OP, FOP |
| 计算分子量 | 43 kDa |
| 观测分子量 | 50 kDa |
| GenBank蛋白编号 | BC011902 |
| 基因名称 | FGFR1OP |
| Gene ID (NCBI) | 11116 |
| RRID | AB_2920217 |
| 偶联类型 | CoraLite® Plus 647 Fluorescent Dye |
| 最大激发/发射波长 | 654 nm / 674 nm |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O95684 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The fibroblast growth factor receptor 1 oncogene partner (FGFR1OP), FOP, is a centrosomal protein that is involved in the anchoring of microtubules to subcellular structures. Three isoforms have been produced by alternative splicing. A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma and progresses to acute myeloid leukemia.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 647 FGFR1OP antibody CL647-11343 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |