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Anti-Human FGFR2/CD332 Rabbit Recombinant Antibody, PBS Only

FGFR2/CD332 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241383D11

Cat no : 98244-1-PBS

Print datasheet

Synonyms

FGFR2, CFD1, CEK3, CD332, BFR 1

验证数据展示

  • FC experiment of Transfected HEK-293T using 98244-1-RR (same clone as 98244-1-PBS)

    FC experiment of Transfected HEK-293T using 98244-1-RR (same clone as 98244-1-PBS)

    1x10^6 HEK-293T cells or FGFR2/CD332 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human FGFR2/CD332 Rabbit Recombinant Antibody (98244-1-RR, Clone: 241383D11) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed. This data was developed using the same antibody clone with 98244-1-PBS in a different storage buffer formulation.

  • FC experiment of Transfected HEK-293T using 98244-1-RR (same clone as 98244-1-PBS)

    FC experiment of Transfected HEK-293T using 98244-1-RR (same clone as 98244-1-PBS)

    1x10^6 HEK-293T cells (left) or FGFR2/CD332 transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Human FGFR2/CD332 Rabbit Recombinant Antibody (98244-1-RR, Clone:241383D11) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were not fixed. This data was developed using the same antibody clone with 98244-1-PBS in a different storage buffer formulation.

产品信息

98244-1-PBS targets FGFR2/CD332 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name fibroblast growth factor receptor 2
Synonyms FGFR2, CFD1, CEK3, CD332, BFR 1
Calculated Molecular Weight92kd
GenBank Accession NumberNM_000141.4
Gene Symbol FGFR2
Gene ID (NCBI) 2263
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP21802
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FGFR2 (Fibroblast growth factor receptor 2), also known as CD332, is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration, and apoptosis. Ligand binding leads to the activation of several signaling pathways, such as RAS, MAPK1/ERK2, MAPK3/ERK1, and the MAP Kinase signaling pathway, as well as the AKT1 signaling pathway. Mutations in the gene of FGFR2 are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis.