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Species Reactivity
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验证数据展示

  • WB analysis of THP-1 using 67152-1-Ig (same clone as 67152-1-PBS)

    WB analysis of THP-1 using 67152-1-Ig (same clone as 67152-1-PBS)

    THP-1 cells were subjected to SDS PAGE followed by western blot with 67152-1-Ig (FGL2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

    IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse spleen tissue using FGL2 antibody (67152-1-Ig, Clone: 2C9C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

    IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse spleen tissue using FGL2 antibody (67152-1-Ig, Clone: 2C9C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

FGL2 Monoclonal antibody, PBS Only

FGL2 Monoclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 67152-1-PBS

产品说明书

CloneNo. 2C9C5

宿主/亚型

Mouse / IgG2b

种属反应性

Human, mouse

应用

WB, IF-P, Indirect ELISA

别名

FGL2, FGL-2, fibrinogen like 2, Fibrinogen like protein 2, Fibroleukin, pT49, T49

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67152-1-PBS targets FGL2 in WB, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 Human, mouse
免疫原 FGL2 fusion protein Ag28619 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 fibrinogen-like 2
别名 FGL2, FGL-2, fibrinogen like 2, Fibrinogen like protein 2, Fibroleukin, pT49, T49
计算分子量 50 kDa
观测分子量 70 kDa
GenBank蛋白编号BC017813
基因名称 FGL2
Gene ID (NCBI) 10875
RRIDAB_2882449
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ14314
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites.