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FGL2 Monoclonal antibody, PBS Only

FGL2 Monoclonal Antibody for WB, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, mouse

Applications

WB, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C9C5

Cat no : 67152-1-PBS

Print datasheet

Synonyms

FGL2, FGL-2, fibrinogen like 2, Fibrinogen like protein 2, Fibroleukin, pT49, T49

验证数据展示

  • WB analysis of THP-1 using 67152-1-Ig (same clone as 67152-1-PBS)

    WB analysis of THP-1 using 67152-1-Ig (same clone as 67152-1-PBS)

    THP-1 cells were subjected to SDS PAGE followed by western blot with 67152-1-Ig (FGL2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

    IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse spleen tissue using FGL2 antibody (67152-1-Ig, Clone: 2C9C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

    IF Staining of mouse spleen using 67152-1-Ig (same clone as 67152-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse spleen tissue using FGL2 antibody (67152-1-Ig, Clone: 2C9C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67152-1-PBS in a different storage buffer formulation.

产品信息

67152-1-PBS targets FGL2 in WB, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB, IF-P, Indirect ELISA Application Description
Tested Reactivity Human, mouse
Immunogen FGL2 fusion protein Ag28619 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name fibrinogen-like 2
Synonyms FGL2, FGL-2, fibrinogen like 2, Fibrinogen like protein 2, Fibroleukin, pT49, T49
Calculated Molecular Weight 50 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC017813
Gene Symbol FGL2
Gene ID (NCBI) 10875
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ14314
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites.