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FH Recombinant antibody, PBS Only

FH Recombinant Antibody for WB,IP,Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, Rat, Mouse

Applications

WB,IP,Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3K16

Cat No : 82508-1-PBS

Print datasheet

Synonyms

FH, Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1

验证数据展示

  • WB analysis using 82508-1-RR (same clone as 82508-1-PBS)

    WB analysis using 82508-1-RR (same clone as 82508-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82508-1-RR (FH antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82508-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse liver using 82508-1-RR (same clone as 82508-1-PBS)

    IP experiment of mouse liver using 82508-1-RR (same clone as 82508-1-PBS)

    IP result of anti-FH (IP:82508-1-RR, 4ug; Detection:82508-1-RR 1:4000) with mouse liver tissue lysate 1840 ug. This data was developed using the same antibody clone with 82508-1-PBS in a different storage buffer formulation.

产品信息

82508-1-PBS targets FH in WB, IP, Indirect ELISA applications and shows reactivity with Human, Rat, Mouse samples.

Tested Applications WB,IP,Indirect ELISA Application Description
Tested Reactivity Human, Rat, Mouse
Immunogen FH fusion protein Ag1934 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name fumarate hydratase
Synonyms FH, Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1
Calculated Molecular Weight 510 aa, 55 kDa
Observed Molecular Weight45 kDa
GenBank Accession NumberBC003108
Gene Symbol FH
Gene ID (NCBI) 2271
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP07954
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

FH(fumarate hydratase) belongs to the class-II fumarase/aspartase family. It is an enzymatic component of the tricarboxylic acid cycle, catalyzing the conversion of fumarate to malate. FH also acts as a tumor suppressor function of FH in sporadic kidney cancer(PMID:21695080). Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.