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FHIT Polyclonal antibody, PBS Only

FHIT Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13362-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 13362-1-AP (same clone as 13362-1-PBS)

    WB analysis using 13362-1-AP (same clone as 13362-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13362-1-AP (FHIT antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13362-1-PBS in a different storage buffer formulation.

产品信息

13362-1-PBS targets FHIT in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen FHIT fusion protein Ag4181 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name fragile histidine triad gene
Synonyms
Calculated Molecular Weight 147 aa, 17 kDa
Observed Molecular Weight15-17 kDa
GenBank Accession NumberBC032336
Gene Symbol FHIT
Gene ID (NCBI) 2272
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP49789
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The candidate tumor suppressor gene, FHIT(Fragile histidine triad protein), encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5'''-P1,P3-triphosphate in vitro and mutation of a central histidine abolishes hydrolase activity(PMID:9391102). FHIT has a major role in regulating beta-catenin-mediated gene transcription.