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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84478-5-RR (same clone as 84478-5-PBS)

    WB analysis using 84478-5-RR (same clone as 84478-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84478-5-RR (FKBP11 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84478-5-PBS in a different storage buffer formulation.

  • IF Staining of Raji using 84478-5-RR (same clone as 84478-5-PBS)

    IF Staining of Raji using 84478-5-RR (same clone as 84478-5-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Raji cells using FKBP11 antibody (84478-5-RR, Clone: 241912G12 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84478-5-PBS in a different storage buffer formulation.

  • WB analysis of mouse pancreas using 84478-5-RR (same clone as 84478-5-PBS)

    WB analysis of mouse pancreas using 84478-5-RR (same clone as 84478-5-PBS)

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 84478-5-RR (FKBP11 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84478-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84478-5-RR

    Affinity and Kinetic Characterization of 84478-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84478-5-RR against Human FKBP11 were performed. The affinity constant is 0.522 nM.

FKBP11 Recombinant antibody, PBS Only

FKBP11 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 84478-5-PBS

产品说明书

CloneNo. 241912G12

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

FK506 binding protein 11, EC:5.2.1.8, 241912G12, 19 kDa FKBP, 19 kDa FK506-binding protein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

84478-5-PBS targets FKBP11 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 FKBP11 fusion protein Ag11368 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 FK506 binding protein 11, 19 kDa
别名 FK506 binding protein 11, EC:5.2.1.8, 241912G12, 19 kDa FKBP, 19 kDa FK506-binding protein
计算分子量 201 aa, 22 kDa
观测分子量24 kDa
GenBank蛋白编号BC027973
基因名称 FKBP11
Gene ID (NCBI) 51303
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ9NYL4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FKBP11 (FK506 binding protein 11, also named FKBP19) was first described as predominantly expressed in secretory tissues including the pancreas and recent studies have suggested a role in beta cell survival under conditions of ER stress (PMID: 35456020). In addition, FKBP11 appears to play a role in osteoblasts and bone formation where it has been observed to associate with interferon-inducible transmembrane protein 5 (IFITM5) (PMID: 24058703).