• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84478-5-RR

    WB analysis using 84478-5-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 84478-5-RR (FKBP11 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

  • IF Staining of Raji using 84478-5-RR

    IF Staining of Raji using 84478-5-RR

    Immunofluorescent analysis of (4% PFA) fixed Raji cells using FKBP11 antibody (84478-5-RR, Clone: 241912G12 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2).

  • WB analysis of mouse pancreas using 84478-5-RR

    WB analysis of mouse pancreas using 84478-5-RR

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 84478-5-RR (FKBP11 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 84478-5-RR

    Affinity and Kinetic Characterization of 84478-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84478-5-RR against Human FKBP11 were performed. The affinity constant is 0.522 nM.

FKBP11 Recombinant antibody

FKBP11 Recombinant Antibody for WB, IF/ICC, ELISA
Cat No. 84478-5-RR

产品说明书

CloneNo. 241912G12

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, ELISA

别名

FK506 binding protein 11, EC:5.2.1.8, 241912G12, 19 kDa FKBP, 19 kDa FK506-binding protein

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive WB detected inmouse stomach tissue, mouse pancreas tissue, rat stomach tissue, mouse liver tissue
Positive IF/ICC detected inRaji cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
Immunofluorescence (IF)/ICCIF/ICC : 1:125-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84478-5-RR targets FKBP11 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 FKBP11 fusion protein Ag11368 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 FK506 binding protein 11, 19 kDa
别名 FK506 binding protein 11, EC:5.2.1.8, 241912G12, 19 kDa FKBP, 19 kDa FK506-binding protein
计算分子量 201 aa, 22 kDa
观测分子量24 kDa
GenBank蛋白编号BC027973
基因名称 FKBP11
Gene ID (NCBI) 51303
RRIDAB_3671999
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ9NYL4
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FKBP11 (FK506 binding protein 11, also named FKBP19) was first described as predominantly expressed in secretory tissues including the pancreas and recent studies have suggested a role in beta cell survival under conditions of ER stress (PMID: 35456020). In addition, FKBP11 appears to play a role in osteoblasts and bone formation where it has been observed to associate with interferon-inducible transmembrane protein 5 (IFITM5) (PMID: 24058703).

实验方案

Product Specific Protocols
WB protocol for FKBP11 antibody 84478-5-RRDownload protocol
IF protocol for FKBP11 antibody 84478-5-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols