验证数据展示
产品信息
84478-6-PBS targets FKBP11 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | FKBP11 fusion protein Ag11368 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | FK506 binding protein 11, 19 kDa |
别名 | FK506 binding protein 11, EC:5.2.1.8, 241912D2, 19 kDa FKBP, 19 kDa FK506-binding protein |
计算分子量 | 201 aa, 22 kDa |
观测分子量 | 24 kDa |
GenBank蛋白编号 | BC027973 |
基因名称 | FKBP11 |
Gene ID (NCBI) | 51303 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q9NYL4 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FKBP11 (FK506 binding protein 11, also named FKBP19) was first described as predominantly expressed in secretory tissues including the pancreas and recent studies have suggested a role in beta cell survival under conditions of ER stress (PMID: 35456020). In addition, FKBP11 appears to play a role in osteoblasts and bone formation where it has been observed to associate with interferon-inducible transmembrane protein 5 (IFITM5) (PMID: 24058703).