FcZero-rAb™ PE Anti-Human FLT3/CD135 Rabbit Recombinant Antibody

FLT3/CD135 FcZero-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

PE Fluorescent Dye

CloneNo.

241414F8

Cat no : PE-FcA98106

Print datasheet

Synonyms

FLT3, FLK2, FL cytokine receptor, Fetal liver kinase-2, EC:2.7.10.1



经过测试的应用

Positive FC detected inReh cells

推荐稀释比

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

PE-FcA98106 targets FLT3/CD135 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name fms-related tyrosine kinase 3
Synonyms FLT3, FLK2, FL cytokine receptor, Fetal liver kinase-2, EC:2.7.10.1
Calculated Molecular Weight 993 aa, 113 kDa
GenBank Accession NumberBC036028
Gene Symbol FLT3
Gene ID (NCBI) 2322
Conjugate PE Fluorescent Dye
Excitation/Emission Maxima Wavelengths496 nm, 565 nm / 578 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.09% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

FLT3 (also known as CD135 or FLK2) is a tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and of dendritic cells. FLT3 was originally identified by its expression in hematopoietic stem/progenitor cells (PMID: 7507245). It is important for the normal development of hematopoietic stem/progenitor cells. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

实验方案

Product Specific Protocols
FC protocol for PE FLT3/CD135 antibody PE-FcA98106Download protocol
Standard Protocols
Click here to view our Standard Protocols