验证数据展示
产品信息
66548-1-PBS targets FMR1 in Indirect ELISA, IP, IHC, WB applications and shows reactivity with rat, mouse, human samples.
经测试应用 | Indirect ELISA, IP, IHC, WB Application Description |
经测试反应性 | rat, mouse, human |
免疫原 | FMR1 fusion protein Ag4697 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | fragile X mental retardation 1 |
别名 | FRAXA, Fragile X messenger ribonucleoprotein 1, Fragile X messenger ribonucleoprotein, fragile X mental retardation 1, FMRP |
计算分子量 | 632 aa, 71 kDa |
观测分子量 | 69-72 kDa |
GenBank蛋白编号 | BC038998 |
基因名称 | FMR1 |
Gene ID (NCBI) | 2332 |
RRID | AB_2881910 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q06787 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The selective RNA-binding protein FMRP forms a messenger ribonucleoprotein complex that associates with polyribosomes, implicating in regulation of translation. FMR1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to and reperss the mRNA. It also has a role in the transport of mRNA from the nucleus to the cytoplasm. FMR1 exists several isforms and the molecular weight of FMR1 is about 59-72 kDa.