• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
  • Featured Product
  • KD/KO Validated

FNTB Monoclonal antibody, PBS Only

FNTB Monoclonal Antibody for WB,IF,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse

Applications

WB,IF,ELISA

Conjugate

Unconjugated

CloneNo.

1F3B10

Cat No : 66783-1-PBS

Print datasheet

Synonyms

FNTB, FPTB, FTase beta

验证数据展示

  • WB analysis using 66783-1-Ig (same clone as 66783-1-PBS)

    WB analysis using 66783-1-Ig (same clone as 66783-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66783-1-Ig (FNTB antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66783-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 66783-1-Ig (same clone as 66783-1-PBS)

    WB analysis of HeLa using 66783-1-Ig (same clone as 66783-1-PBS)

    WB result of FNTB antibody (66783-1-Ig; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FNTB transfected HeLa cells. This data was developed using the same antibody clone with 66783-1-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 66783-1-Ig (same clone as 66783-1-PBS)

    IF Staining of A431 using 66783-1-Ig (same clone as 66783-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using FNTB antibody (66783-1-Ig, Clone: 1F3B10 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66783-1-PBS in a different storage buffer formulation.

产品信息

66783-1-PBS targets FNTB in WB, IF, ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB,IF,ELISA Application Description
Tested Reactivity Human, mouse
Immunogen FNTB fusion protein Ag27796 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name farnesyltransferase, CAAX box, beta
Synonyms FNTB, FPTB, FTase beta
Calculated Molecular Weight 437 aa, 49 kDa
Observed Molecular Weight 44-45 kDa
GenBank Accession NumberBC020232
Gene Symbol FNTB
Gene ID (NCBI) 2342
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP49356
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

背景介绍

FNTB is the catalytic β subunit of farnesyltransferase which is an alpha/beta heterodimeric enzyme attaching a farnesyl group to a single cysteine in several cellular proteins like RAS and facilitating their translocation from the cytoplasm to the plasma membrane. Farnesyltransferase inhibitors have been developed as ant-tumor agents. FNTB is required for the homeostasis of skin keratinocytes.