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  • Featured Product
  • KD/KO Validated

FOLR1 Monoclonal antibody, PBS Only

FOLR1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2B4B7

Cat no : 60307-1-PBS

Print datasheet

Synonyms

Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1 (adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha, KB cells FBP, MOv18

验证数据展示

  • WB analysis of HeLa using 60307-1-Ig (same clone as 60307-1-PBS)

    WB analysis of HeLa using 60307-1-Ig (same clone as 60307-1-PBS)

    WB result of FOLR1 antibody (60307-1-Ig, 1:4000) with si-Control and si-FOLR1 transfected HeLa cells.. This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • WB analysis of human milk using 60307-1-Ig (same clone as 60307-1-PBS)

    WB analysis of human milk using 60307-1-Ig (same clone as 60307-1-PBS)

    human milk were subjected to SDS PAGE followed by western blot with 60307-1-Ig (FOLR1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 60307-1-Ig (FOLR1 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 60307-1-Ig (FOLR1 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

产品信息

60307-1-PBS targets FOLR1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen FOLR1 fusion protein Ag19959 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name folate receptor 1 (adult)
Synonyms Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1 (adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha, KB cells FBP, MOv18
Calculated Molecular Weight 257 aa, 30 kDa
Observed Molecular Weight 36-38 kDa
GenBank Accession NumberBC002947
Gene Symbol FOLR1
Gene ID (NCBI) 2348
RRIDAB_2881421
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP15328
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Folate receptor 1 (FOLR1), also known as folate receptor alpha or adult folate-binding protein (FBP), is a 38-kDa glycoprotein belonging to the folate receptor family (PMID:15094207; 23528302). The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung, kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer, non-small cell lung cancer, breast cancer, kidney cancer and high-grade osteosarcoma (PMID: 23528302; 23357463).