• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of HeLa using 60307-1-Ig (same clone as 60307-1-PBS)

    WB analysis of HeLa using 60307-1-Ig (same clone as 60307-1-PBS)

    WB result of FOLR1 antibody (60307-1-Ig, 1:4000) with si-Control and si-FOLR1 transfected HeLa cells.. This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • WB analysis of human milk using 60307-1-Ig (same clone as 60307-1-PBS)

    WB analysis of human milk using 60307-1-Ig (same clone as 60307-1-PBS)

    human milk were subjected to SDS PAGE followed by western blot with 60307-1-Ig (FOLR1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 60307-1-Ig (FOLR1 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 60307-1-Ig (FOLR1 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

FOLR1 Monoclonal antibody, PBS Only

FOLR1 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60307-1-PBS

产品说明书

CloneNo. 2B4B7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1 (adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha, KB cells FBP, MOv18

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

60307-1-PBS targets FOLR1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 FOLR1 fusion protein Ag19959 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 folate receptor 1 (adult)
别名 Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1 (adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha, KB cells FBP, MOv18
计算分子量 257 aa, 30 kDa
观测分子量 36-38 kDa
GenBank蛋白编号BC002947
基因名称 FOLR1
Gene ID (NCBI) 2348
RRIDAB_2881421
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP15328
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Folate receptor 1 (FOLR1), also known as folate receptor alpha or adult folate-binding protein (FBP), is a 38-kDa glycoprotein belonging to the folate receptor family (PMID:15094207; 23528302). The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung, kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer, non-small cell lung cancer, breast cancer, kidney cancer and high-grade osteosarcoma (PMID: 23528302; 23357463).