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验证数据展示

  • IF Staining of human liver using CL488-66753

    IF Staining of human liver using CL488-66753

    Immunofluorescent analysis of (4% PFA) fixed human liver tissue using CoraLite® Plus 488 Factor X antibody (CL488-66753, Clone: 3D3F11 ) at dilution of 1:200.

CoraLite® Plus 488-conjugated Factor X Monoclonal antibody

Factor X Monoclonal Antibody for IF-P
Cat No. CL488-66753

产品说明书

CloneNo. 3D3F11

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

IF-P

别名

coagulation factor X, F10, FX, FXA, Stuart factor, Stuart Prower factor

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inhuman liver tissue
For other applications, we recommend the unconjugated version of this antibody, 66753-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-66753 targets Factor X in IF-P applications and shows reactivity with Human samples.

经测试应用 IF-P Application Description
经测试反应性 Human
免疫原 Factor X fusion protein Ag11664 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 coagulation factor X
别名 coagulation factor X, F10, FX, FXA, Stuart factor, Stuart Prower factor
计算分子量 488 aa, 55 kDa
观测分子量 50 kDa
GenBank蛋白编号BC046125
基因名称 F10
Gene ID (NCBI) 2159
RRIDAB_2934494
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP00742
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Coagulation factor X (F10) is a vitamin K-dependent glycoprotein that participates in the middle phase of the blood coagulation cascade (PMID: 1931959; 1313796). It is synthesized as a single-chain precursor in the liver where it undergoes a number of covalent processing steps before secretion into the blood as a two-chain molecule linked by a disulfide bond (PMID: 1313796). The light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. Factor X is activated into factor Xa, by both the extrinsic and intrinsic pathway. The activated factor then converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Factor X antibody CL488-66753Download protocol
Standard Protocols
Click here to view our Standard Protocols