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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67944-1-Ig (same clone as 67944-1-PBS)

    WB analysis using 67944-1-Ig (same clone as 67944-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67944-1-Ig (FcRn antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67944-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 67944-1-Ig (same clone as 67944-1-PBS)

    IHC staining of human liver using 67944-1-Ig (same clone as 67944-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 67944-1-Ig (FcRn antibody) at dilution of 1:10000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67944-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 67944-1-Ig (same clone as 67944-1-PBS)

    IHC staining of human liver using 67944-1-Ig (same clone as 67944-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 67944-1-Ig (FcRn antibody) at dilution of 1:10000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67944-1-PBS in a different storage buffer formulation.

FcRn Monoclonal antibody, PBS Only

FcRn Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67944-1-PBS

产品说明书

CloneNo. 2H4A5

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, IHC, Indirect ELISA

别名

alpha chain, FCGRT, FCRN, Neonatal Fc receptor

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67944-1-PBS targets FcRn in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human
免疫原 FcRn fusion protein Ag31173 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 Fc fragment of IgG, receptor, transporter, alpha
别名 alpha chain, FCGRT, FCRN, Neonatal Fc receptor
计算分子量 40 kDa
观测分子量 35-40 kDa
GenBank蛋白编号BC008734
基因名称 FcRn
Gene ID (NCBI) 2217
RRIDAB_2918696
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP55899
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The neonatal Fc receptor for IgG (FcRn) is a membrane-associated receptor which acts as a key determinant of IgG homeostasis. FcRn is similar in structure to major histocompatibility class I molecules. It is a heterodimer composed of a alpha chain associated with β2-microglobulin. FcRn transfers IgG from the mother to the fetus across the placenta and the proximal small intestine. In addition, throughout life, FcRn protects IgG from degradation and thus regulates the serum half-life of IgG (PMID: 17703228).