验证数据展示
产品信息
66158-1-PBS targets Fibrinogen Gamma Chain in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IF/ICC, ELISA Application Description |
经测试反应性 | human |
免疫原 | Fibrinogen Gamma Chain fusion protein Ag8817 种属同源性预测 |
宿主/亚型 | Mouse / IgM |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | fibrinogen gamma chain |
别名 | FGG, PRO2061, 2B2B8 |
计算分子量 | 453aa,52 kDa; 437aa,50 kDa |
观测分子量 | 52 kDa |
GenBank蛋白编号 | BC007044 |
基因名称 | Fibrinogen Gamma Chain |
Gene ID (NCBI) | 2266 |
RRID | AB_2881554 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P02679 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGG is the gamma chain of fibrinogen. Mutations in the gene of FGG lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.