验证数据展示
产品信息
66158-1-PBS targets Fibrinogen Gamma Chain in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IHC, IF/ICC, ELISA Application Description |
Tested Reactivity | human |
Immunogen | Fibrinogen Gamma Chain fusion protein Ag8817 种属同源性预测 |
Host / Isotype | Mouse / IgM |
Class | Monoclonal |
Type | Antibody |
Full Name | fibrinogen gamma chain |
Synonyms | FGG, PRO2061, 2B2B8 |
Calculated Molecular Weight | 453aa,52 kDa; 437aa,50 kDa |
Observed Molecular Weight | 52 kDa |
GenBank Accession Number | BC007044 |
Gene Symbol | Fibrinogen Gamma Chain |
Gene ID (NCBI) | 2266 |
RRID | AB_2881554 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P02679 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGG is the gamma chain of fibrinogen. Mutations in the gene of FGG lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.