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  • Featured Product
  • KD/KO Validated

Fibromodulin Monoclonal antibody, PBS Only

Fibromodulin Monoclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3E9D10

Cat no : 60108-1-PBS

Print datasheet

Synonyms

fibromodulin, FM, FMOD, KSPG fibromodulin, SLRR2E

验证数据展示

  • IHC staining of human hepatocirrhosis using 60108-1-Ig (same clone as 60108-1-PBS)

    IHC staining of human hepatocirrhosis using 60108-1-Ig (same clone as 60108-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 60108-1-Ig (Fibromodulin antibody) at dilution of 1:300 (under 10x lens). This data was developed using the same antibody clone with 60108-1-PBS in a different storage buffer formulation.

  • IHC staining of human hepatocirrhosis using 60108-1-Ig (same clone as 60108-1-PBS)

    IHC staining of human hepatocirrhosis using 60108-1-Ig (same clone as 60108-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 60108-1-Ig (Fibromodulin antibody) at dilution of 1:300 (under 40x lens). This data was developed using the same antibody clone with 60108-1-PBS in a different storage buffer formulation.

产品信息

60108-1-PBS targets Fibromodulin in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Fibromodulin fusion protein Ag4030 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name fibromodulin
Synonyms fibromodulin, FM, FMOD, KSPG fibromodulin, SLRR2E
Calculated Molecular Weight 376 aa, 43 kDa
GenBank Accession NumberBC035281
Gene Symbol Fibromodulin
Gene ID (NCBI) 2331
RRIDAB_2105538
Conjugate Unconjugated
Form Liquid
Purification MethodCaprylic acid/ammonium sulfate precipitation
UNIPROT IDQ06828
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fibromodulin (FMOD), an extracellular matrix protein, belongs to the small leucine-rich proteoglycan family. Fibromodulin is a collagen-binding protein present in many types of connective tissues, e.g. cartilage, tendon, skin, sclera and cornea (PMID: 2531085). It is involved in fibrillogenesis, cell adhesion, and cytokine activity modulation (PMID: 15741214). Fibromodulin may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. The calculated molecular mass of fibromodulin is 43 kDa, extracellular fibromodulin appears as one single band of 59 kDa due to glycosylation (PMID: 2531085; 22138190).