验证数据展示
产品信息
21136-1-PBS targets Fibulin-7 in WB, Indirect ELISA applications and shows reactivity with human, pig samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, pig |
免疫原 | Fibulin-7 fusion protein Ag15564 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | fibulin 7 |
别名 | |
计算分子量 | 439 aa, 47 kDa |
观测分子量 | 47 kDa |
GenBank蛋白编号 | BC035784 |
基因名称 | Fibulin-7 |
Gene ID (NCBI) | 129804 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen Affinity purified |
UNIPROT ID | Q53RD9 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Fibulins are a family of extracellular matrix glycoproteins associated with basement membranes, elastic fibers, and other matrices (PMID: 19189051). The family members are defined by the presence of two structural modules, a tandem repeat of epidermal growth factor-like modules, and a unique C-terminal fibulin-type module (PMID: 19189051). They play an important role in regulating multiple cellular functions such as adhesion, growth, motility, and survival (PMID: 32429873). Fibulin-7, also named as TM14, was first identified in the mouse tooth germ cDNA microarray by differential hybridization (PMID: 17699513). Fibulin-7 is expressed in developing odontoblasts, in the giant trophoblast layer of the placenta, in the choroid of the eyes as well as in the cartilage (PMID: 32429873). It plays important roles in both the differentiation and maintenance of odontoblasts as well as in dentin formation.