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CoraLite® Plus 488-conjugated Follistatin Monoclonal antibody

Follistatin Monoclonal Antibody for IF/ICC
Cat No. CL488-60060

产品说明书

CloneNo. 4E9B10

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse

应用

IF/ICC

Activin binding protein, follistatin, FS, FST

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inHeLa cells
For other applications, we recommend the unconjugated version of this antibody, 60060-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-60060 targets Follistatin in IF/ICC applications and shows reactivity with human, mouse samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse
免疫原 Follistatin fusion protein Ag0775 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 follistatin
别名 Activin binding protein, follistatin, FS, FST
计算分子量 33 aa, 7 kDa
观测分子量 35 kDa
GenBank蛋白编号BC004107
基因名称 Follistatin
Gene ID (NCBI) 10468
RRIDAB_2883093
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Caprylic Acid-Ammonium Sulfate Precipitation
UNIPROT IDP19883
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Follistatin (FST) is a member of the tissue growth factor β family and is a secreted glycoprotein that antagonizes many members of the family, including activin A, growth differentiation factor11 , and myostatin. It binds activin A with high affinity and whose expression can be induced by activin A and several other pro-inflammatory cytokines. Activin A-follistatin complexes are biologically inactive and bind to cell surface heparan sulphate-containing proteoglycans for internalisation and degradation. It has also been found to play a significant role in the management of skeletal muscle size and mass. It also has important roles in early embryonic development, differentiation of ovarian granulosa cells, liver fibrosis and polycystic ovarian syndrome.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Follistatin antibody CL488-60060Download protocol
Standard Protocols
Click here to view our Standard Protocols
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