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GABRG2 Polyclonal antibody, PBS Only

GABRG2 Polyclonal Antibody for WB, IF-P, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF-P, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 14104-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 14104-1-AP (same clone as 14104-1-PBS)

    WB analysis using 14104-1-AP (same clone as 14104-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14104-1-AP (GABRG2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14104-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 14104-1-AP (same clone as 14104-1-PBS)

    IP experiment of mouse brain using 14104-1-AP (same clone as 14104-1-PBS)

    IP result of anti-GABRG2 (IP:14104-1-AP, 4ug; Detection:14104-1-AP 1:500) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 14104-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse cerebellum using 14104-1-AP (same clone as 14104-1-PBS)

    IF Staining of mouse cerebellum using 14104-1-AP (same clone as 14104-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse cerebellum tissue using GABRG2 antibody (14104-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 14104-1-PBS in a different storage buffer formulation.

产品信息

14104-1-PBS targets GABRG2 in WB, IF-P, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IF-P, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen GABRG2 fusion protein Ag5237 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name gamma-aminobutyric acid (GABA) A receptor, gamma 2
Synonyms
Calculated Molecular Weight 467 aa, 54 kDa
Observed Molecular Weight 54-60 kDa
GenBank Accession NumberBC059389
Gene Symbol GABRG2
Gene ID (NCBI) 2566
RRIDAB_10693527
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP18507
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2), which is expected to be located in cell membrane and expressed in brain and retina. The calculated molecular weight of the protein is 54 kDa. This antibody can recognize the 43 kDa band of target (PMID:12091434). And it also has glycosylation modification. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures.