验证数据展示
产品信息
14104-1-PBS targets GABRG2 in WB, IF-P, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IF-P, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | GABRG2 fusion protein Ag5237 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
别名 | |
计算分子量 | 467 aa, 54 kDa |
观测分子量 | 54-60 kDa |
GenBank蛋白编号 | BC059389 |
基因名称 | GABRG2 |
Gene ID (NCBI) | 2566 |
RRID | AB_10693527 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P18507 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2), which is expected to be located in cell membrane and expressed in brain and retina. The calculated molecular weight of the protein is 54 kDa. This antibody can recognize the 43 kDa band of target (PMID:12091434). And it also has glycosylation modification. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures.