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GATM Monoclonal antibody, PBS Only

GATM Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1D12G5

Cat no : 68513-1-PBS

Print datasheet

Synonyms

Transamidinase, L-arginine:glycine amidinotransferase, EC:2.1.4.1, AGAT, 1D12G5

验证数据展示

  • WB analysis of pig kidney using 68513-1-Ig (same clone as 68513-1-PBS)

    WB analysis of pig kidney using 68513-1-Ig (same clone as 68513-1-PBS)

    pig kidney tissue were subjected to SDS PAGE followed by western blot with 68513-1-Ig (GATM antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68513-1-PBS in a different storage buffer formulation.

  • WB analysis using 68513-1-Ig (same clone as 68513-1-PBS)

    WB analysis using 68513-1-Ig (same clone as 68513-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68513-1-Ig (GATM antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68513-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy GATM Ready-To-Use IHC Kit. GATM primary antibody included.

产品信息

68513-1-PBS targets GATM in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat, pig
Immunogen GATM fusion protein Ag3754 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Synonyms Transamidinase, L-arginine:glycine amidinotransferase, EC:2.1.4.1, AGAT, 1D12G5
Calculated Molecular Weight 423 aa, 48 kDa
Observed Molecular Weight48 kDa
GenBank Accession NumberBC004141
Gene Symbol GATM
Gene ID (NCBI) 2628
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP50440
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GATM, also known as AGAT, produces ornithine and guanidinoacetate (GAA) from arginine and glycine, and is a key enzyme for creatine synthesis. GATM deficiency in early infancy causes neurodevelopmental delay. GATM is predominantly expressed in kidney and pancreas in adults. Decrease of GAMT proteins was observed in proximal tubule damage cases, which links GATM as a general marker for proximal tubule damage. Alternative splicing of GATM generates three isoforms with molecular weights between 44 kDa to 48 kDa.