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验证数据展示

  • WB analysis of pig kidney using 68513-1-Ig (same clone as 68513-1-PBS)

    WB analysis of pig kidney using 68513-1-Ig (same clone as 68513-1-PBS)

    pig kidney tissue were subjected to SDS PAGE followed by western blot with 68513-1-Ig (GATM antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68513-1-PBS in a different storage buffer formulation.

  • WB analysis using 68513-1-Ig (same clone as 68513-1-PBS)

    WB analysis using 68513-1-Ig (same clone as 68513-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68513-1-Ig (GATM antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68513-1-PBS in a different storage buffer formulation.

GATM Monoclonal antibody, PBS Only

GATM Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68513-1-PBS

产品说明书

CloneNo. 1D12G5

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat, pig

应用

WB, Indirect ELISA

别名

Transamidinase, L-arginine:glycine amidinotransferase, EC:2.1.4.1, AGAT, 1D12G5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy GATM Ready-To-Use IHC Kit. GATM primary antibody included.

产品信息

68513-1-PBS targets GATM in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat, pig
免疫原 GATM fusion protein Ag3754 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 glycine amidinotransferase (L-arginine:glycine amidinotransferase)
别名 Transamidinase, L-arginine:glycine amidinotransferase, EC:2.1.4.1, AGAT, 1D12G5
计算分子量 423 aa, 48 kDa
观测分子量48 kDa
GenBank蛋白编号BC004141
基因名称 GATM
Gene ID (NCBI) 2628
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP50440
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GATM, also known as AGAT, produces ornithine and guanidinoacetate (GAA) from arginine and glycine, and is a key enzyme for creatine synthesis. GATM deficiency in early infancy causes neurodevelopmental delay. GATM is predominantly expressed in kidney and pancreas in adults. Decrease of GAMT proteins was observed in proximal tubule damage cases, which links GATM as a general marker for proximal tubule damage. Alternative splicing of GATM generates three isoforms with molecular weights between 44 kDa to 48 kDa.